Chemistry

Chemistry is a versatile subject area and the pursuit of a career in chemistry can be a most intellectually satisfying experience. No other basic science touches and shapes as many aspects of modern society as does chemistry. The study of chemistry has provided solutions to complex problems and has improved the quality of all phases of human life from soft contact lenses and synthetic blood to longer-lasting paint and alternative fuels. A particular strength of this department is in surface and interface chemistry, which bridges many areas of modern science and technology.

Chemists at all levels of education find a market for their skills and knowledge in many employment areas. Chemists provide the technical backbone for the manufacturing industries (pharmaceuticals, plastics, paper, semiconductor electronics technology, and agriculture), for service industries (clinical and forensic laboratories, academe, environmental protection, and information science) and for governmental positions in regulatory agencies and in science policy analyses. Many chemists are employed in nontraditional areas, such as patent law, insurance underwriting, sales, product management, journalism, and even banking.

The alluring challenge of chemistry inspires many bachelor degree recipients to study for advanced degrees within the discipline of chemistry and in other areas, as well. Chemistry or biochemistry is the strongest preparation for graduate studies or for professional school in the health-related disciplines (medicine, pharmacology, and biochemistry), and for other science programs (materials science, polymers, biotechnology, environmental studies, and mineralogy).

The study of chemistry opens doors to satisfying careers, to a stimulating view of the world, and to a professional life in which one’s natural tendency to ask “Why?” can lead to personally rewarding endeavors. The undergraduate curriculum in chemistry contains many of the prerequisites for biology, earth and environmental sciences, materials science, molecular biology, physics, and chemical engineering. This allows students to transfer credits among these majors through the sophomore year.

Chemistry students have the opportunity to design their undergraduate curricula for specialization in a variety of fields through the choice of both degree program and some additional courses.

Degree Programs

The Department of Chemistry offers undergraduate degrees in both the College of Arts and Sciences and the Rossin College of Engineering and Applied Sciences. Students in the College of Arts and Sciences have three options: the B. S. in Chemistry, the B. A. in Chemistry, and the B. S. in Pharmaceutical Chemistry. In addition we offer an interdepartmental B. S. in Biochemistry in collaboration with the Department of Biological Sciences. For students in the College of Engineering and Applied Sciences we offer the B. S. in Chemistry.

In the College of Arts and Sciences, the traditional degree certified by the American Chemical Society is offered; the B. S. degree in the College of Engineering is the ACS certified degree and is identical in terms of degree program requirements, but the college level requirements are different. All B. S. programs share several common "core" chemistry courses, and have similar collateral science requirements. although the options are different depending on the specific degree program chosen. The B.S. programs are pre-professional in nature, and students planning to attend graduate school in chemistry or an allied science should elect the ACS certified B. S. program in the college to which they have been admitted. The traditional B. A. Program in the College of Arts and Sciences is not a pre-professional program and may be elected by students who do not plan to do graduate work in chemistry or allied sciences but who desire a stronger background in chemistry than is provided by a chemistry minor.

In addition to the traditional certified B. S degree and B. A. degrees, a regular non-ACS certified B. S. Chemistry program is available in the College of Arts and Sciences. Students may transfer from a B. S. program to a B. A. program easily, but the reverse is more difficult, considering both the number of required chemistry courses and the more restrictive collateral courses in Mathematics and Physics. Students in a B. A. program who make the decision to attend graduate school in chemistry or allied sciences can achieve a minimum preparation for this transition by electing CHM 307 Advanced Inorganic Chemistry as an additional course, and by taking additional 300 level chemistry courses.

The Department of Chemistry also offers a Ph.D. in Chemistry for qualified students -- see the Graduate Tab.

Degrees in the College of Arts and Sciences

In the College of Arts and Sciences the Chemistry Department offers three degrees: a B.S. in Chemistry, a B.A. in Chemistry and a B.S. in Pharmaceutical Chemistry with an interdepartmental B.S. in Biochemistry degree with the Department of Biological Sciences. The B.S. in Chemistry degree has two tracks: 1) the American Chemical Society accredited B.S. in Chemistry degree, and 2) a B.S. in Chemistry degree that is not accredited that requires fewer credits. All degree programs require appropriate Mathematics and Physics collateral courses, and some require an introduction to programming course.

With regard to the B.S. in Pharmaceutical Chemistry, the pharmaceutical industry is focused on exploring the biochemistry of disease and designing or finding drugs to cure or ameliorate disease. Biochemists, organic chemists, biologists, and chemical engineers collaborate to achieve this end. The majority of chemists hired today go into the pharmaceutical industry. The B.S. in Pharmaceutical Chemistry is a chemistry degree option which focuses on core chemistry, biochemistry, and molecular biology to prepare students for careers in this field. Since it is a highly interdisciplinary field it requires the breadth of knowledge offered by this degree program.

Common "core" Chemistry courses

The following courses are required for ANY of the undergraduate degree programs administered by the Department of Chemistry (not Biochemistry). One of the general chemistry sequences is taken in the first year, with organic chemistry in the second year. Most of the required chemistry courses are at the 300 level, and are distributed between the third and fourth years.

Select one of the following:		8
CHM 040 & CHM 041	Honors General Chemistry I and Honors General Chemistry II
or
CHM 030 & CHM 031	Introduction to Chemical Principles and Chemical Equilibria in Aqueous Systems
CHM 110 & CHM 111	Organic Chemistry I and Organic Chemistry Laboratory I	4
CHM 112 & CHM 113	Organic Chemistry II and Organic Chemistry Laboratory II	4
CHM 332	Analytical Chemistry	3
Concentrations (see below)		3-8
CHM 307	Advanced Inorganic Chemistry	3
CHM 351	Professional Development Seminar	2
Total Credits		27-32

Collateral requirements

The B.S. in Chemistry degree programs require Path A below for the collateral requirements. The B.S. in Pharmaceutical Chemistry, the B.A. in Chemistry, and the B.S. in Biochemistry requires EITHER Path A or Patch B. A course from Path A may replace a course in Path B, but the opposite is not true. Thus it is suggested that students consider the MATH 21, 22, 23 sequence if a B.S. in Chemistry degree program is one of their options.

Path A
MATH 021	Calculus I	4
MATH 022	Calculus II	4
MATH 023	Calculus III	4
MATH 205	Linear Methods	3
PHY 011 & PHY 012	Introductory Physics I and Introductory Physics Laboratory I	5
PHY 021 & PHY 022	Introductory Physics II and Introductory Physics Laboratory II	5
ENGR 010	Applied Engineering Computer Methods	2
or CSE 003	Introduction to Programming, Part A
Total Credits		27

Path B
MATH 051	Survey of Calculus I	4
MATH 052	Survey of Calculus II	3
MATH 043	Survey of Linear Algebra	3
PHY 010 & PHY 012	General Physics I and Introductory Physics Laboratory I	5
PHY 013 & PHY 022	General Physics II and Introductory Physics Laboratory II	4
Total Credits		19

Specializations

The table directly below lists the course requirements for the two B.S. degrees. It should be noted that the ACS Certified Degree is the "gold standard" and is the best degree program to prepare for graduate work in Chemistry or a closely related field.

B.S. Chemistry (ACS certified Degree)

CHM 040	Honors General Chemistry I	4
or CHM 030	Introduction to Chemical Principles
CHM 041	Honors General Chemistry II	4
or CHM 031	Chemical Equilibria in Aqueous Systems
CHM 110 & CHM 111	Organic Chemistry I and Organic Chemistry Laboratory I	4
CHM 112 & CHM 113	Organic Chemistry II and Organic Chemistry Laboratory II	4
CHM 307	Advanced Inorganic Chemistry	3
CHM 332	Analytical Chemistry	3
CHM 334	Advanced Chemistry Laboratory I	3
CHM 335	Advanced Chemistry Laboratory II	3
CHM 341	Molecular Structure, Bonding and Dynamics	3
CHM 342	Thermodynamics & Kinetics	3
CHM 343	Physical Chemistry Laboratory	2
CHM 351	Professional Development Seminar	2
CHM 371	Elements of Biochemistry I	3
CHM 375	Research Chemistry Laboratory	2
Advanced Chemistry Elective Requirement
Select one course from two of the three areas listed below:		6
Analytical Chemistry (CHM 350) ¹
CHM 336	Clinical Chemistry
CHM 356	Spectral Analysis
CHM 388	Polymer Characterization
Biochemistry (CHM 350) ¹
CHM 323	Chemical Biology
CHM 362	Molecular Biophysics
CHM 365	Protein Separation & Biophysical Analysis
CHM 372	Elements of Biochemistry II
CHM 373	Lipids and Membranes
CHM 377	Biochemistry Laboratory
Inorganic Chemistry (CHM 350) ¹
CHM 305	Organometallic Chemistry
CHM 337	Crystallography and Diffraction
CHM 340	Solid-State Chemistry
CHM 364	Bioinorganic Chemistry
Collateral Requirements
MATH 021	Calculus I	4
MATH 022	Calculus II	4
MATH 023	Calculus III	4
MATH 205	Linear Methods	3
PHY 011 & PHY 012	Introductory Physics I and Introductory Physics Laboratory I	5
PHY 021 & PHY 022	Introductory Physics II and Introductory Physics Laboratory II	5
Select one from the following:		2-4
ENGR 010	Applied Engineering Computer Methods
CSE 003	Introduction to Programming, Part A
CSE 007	Introduction to Programming
Total Credits		76-78

¹: CHM 350 may be applied to any one of the three areas, provided it is for a 3 credit lecture course and the particular section has been identified to fit into one of these three areas based on course content. CHM 350 may be repeated for credit if a different topic is offered, and if appropriate, a second CHM 350 section may count under a different area.

B.S. Chemistry- Analytical/Physical Concentration

CHM 040	Honors General Chemistry I	4
or CHM 030	Introduction to Chemical Principles
CHM 041	Honors General Chemistry II	4
or CHM 031	Chemical Equilibria in Aqueous Systems
CHM 110 & CHM 111	Organic Chemistry I and Organic Chemistry Laboratory I	4
CHM 112 & CHM 113	Organic Chemistry II and Organic Chemistry Laboratory II	4
CHM 307	Advanced Inorganic Chemistry	3
CHM 332	Analytical Chemistry	3
CHM 334	Advanced Chemistry Laboratory I	3
CHM 335	Advanced Chemistry Laboratory II	3
CHM 341	Molecular Structure, Bonding and Dynamics	3
CHM 342	Thermodynamics & Kinetics	3
CHM 343	Physical Chemistry Laboratory	2
CHM 351	Professional Development Seminar	2
Collateral Requirements
MATH 021	Calculus I	4
MATH 022	Calculus II	4
MATH 023	Calculus III	4
MATH 205	Linear Methods	3
PHY 011 & PHY 012	Introductory Physics I and Introductory Physics Laboratory I	5
PHY 021 & PHY 022	Introductory Physics II and Introductory Physics Laboratory II	5
Select one of the following:		2-4
ENGR 010	Applied Engineering Computer Methods
CSE 003	Introduction to Programming, Part A
CSE 007	Introduction to Programming
Total Credits		65-67

B. A. Chemistry

The B.A. in Chemistry degree program is considerably less rigorous than either track under the B.S. in Chemistry degree, but is sometimes chosen as a second major to pair with another major in a single B.A. degree. Note the choices in the collateral courses that clearly indicate either Path A or Path B may be chosen for these non-chemistry required courses.

CHM 040	Honors General Chemistry I	4
or CHM 030	Introduction to Chemical Principles
CHM 041	Honors General Chemistry II	4
or CHM 031	Chemical Equilibria in Aqueous Systems
CHM 110 & CHM 111	Organic Chemistry I and Organic Chemistry Laboratory I	4
CHM 112 & CHM 113	Organic Chemistry II and Organic Chemistry Laboratory II	4
Select one of the follwoing:		3
CHM 194	Physical Chemistry for Biological Sciences
CHM 342	Thermodynamics & Kinetics
CHM 307	Advanced Inorganic Chemistry	3
CHM 332	Analytical Chemistry	3
CHM 343	Physical Chemistry Laboratory	2
CHM 351	Professional Development Seminar	2
Advanced CHM elective (300 Level)		3
Select one of the following:
CHM 305	Organometallic Chemistry
CHM 323	Chemical Biology
CHM 334	Advanced Chemistry Laboratory I
CHM 336	Clinical Chemistry
CHM 337	Crystallography and Diffraction
CHM 340	Solid-State Chemistry
CHM 341	Molecular Structure, Bonding and Dynamics
CHM 346	Photochemistry of Consequence
CHM 350	Special Topics
CHM 356	Spectral Analysis
CHM 357	Organic Reaction Mechanisms
CHM 358	Advanced Organic Chemistry
CHM 362	Molecular Biophysics
CHM 364	Bioinorganic Chemistry
CHM 365	Protein Separation & Biophysical Analysis
CHM 371	Elements of Biochemistry I
CHM 372	Elements of Biochemistry II
CHM 373	Lipids and Membranes
CHM 375	Research Chemistry Laboratory
CHM 376	Advanced Research Chemistry Laboratory
CHM 377	Biochemistry Laboratory
CHM 388	Polymer Characterization
CHM 391	Colloid and Surface Chemistry
CHM 393	Physical Polymer Science
CHM 394	Organic Polymer Science I
Collateral Requirements		19-21
MATH 021	Calculus I
or MATH 051	Survey of Calculus I
MATH 022	Calculus II
or MATH 052	Survey of Calculus II
MATH 205	Linear Methods
or MATH 043	Survey of Linear Algebra
PHY 011	Introductory Physics I
or PHY 010	General Physics I
PHY 012	Introductory Physics Laboratory I
PHY 021	Introductory Physics II
or PHY 013	General Physics II
PHY 022	Introductory Physics Laboratory II
Total Credits		51-53

B.S. Pharmaceutical Chemistry

The B.S. in Pharmaceutical Chemistry has some required Biological Science courses as background for entry into the field. As a consequence, there are fewer Chemistry courses, and they are tailored to the requirements of the pharmaceutical industry. Note the flexibility in the collateral requirements is the same as for the B.A. degree.

CHM 040	Honors General Chemistry I	4
or CHM 030	Introduction to Chemical Principles
CHM 041	Honors General Chemistry II	4
or CHM 031	Chemical Equilibria in Aqueous Systems
CHM 110 & CHM 111	Organic Chemistry I and Organic Chemistry Laboratory I	4
CHM 112 & CHM 113	Organic Chemistry II and Organic Chemistry Laboratory II	4
Select one of the following:		3
CHM 194	Physical Chemistry for Biological Sciences
CHM 342	Thermodynamics & Kinetics
CHM 307	Advanced Inorganic Chemistry	3
CHM 332	Analytical Chemistry	3
CHM 351	Professional Development Seminar	2
CHM 358	Advanced Organic Chemistry	3
CHM 371	Elements of Biochemistry I	3
CHM 372	Elements of Biochemistry II	3
Advanced CHM Elective (300 Level)		3
Select one of the following:
CHM 305	Organometallic Chemistry
CHM 323	Chemical Biology
CHM 334	Advanced Chemistry Laboratory I
CHM 336	Clinical Chemistry
CHM 337	Crystallography and Diffraction
CHM 340	Solid-State Chemistry
CHM 341	Molecular Structure, Bonding and Dynamics
CHM 346	Photochemistry of Consequence
CHM 350	Special Topics
CHM 356	Spectral Analysis
CHM 357	Organic Reaction Mechanisms
CHM 362	Molecular Biophysics
CHM 364	Bioinorganic Chemistry
CHM 365	Protein Separation & Biophysical Analysis
CHM 373	Lipids and Membranes
CHM 375	Research Chemistry Laboratory
CHM 376	Advanced Research Chemistry Laboratory
CHM 377	Biochemistry Laboratory
CHM 388	Polymer Characterization
CHM 391	Colloid and Surface Chemistry
CHM 393	Physical Polymer Science
CHM 394	Organic Polymer Science I
Biological Sciences
BIOS 041 & BIOS 042	Introduction to Cellular and Molecular Biology and Introduction to Cellular and Molecular Biology Laboratory	4
BIOS 115	Genetics	3
Collateral Requirements		19-21
MATH 012	Basic Statistics and Data Science ¹
MATH 021	Calculus I
or MATH 051	Survey of Calculus I
MATH 022	Calculus II
or MATH 052	Survey of Calculus II
MATH 205	Linear Methods
or MATH 043	Survey of Linear Algebra
PHY 011	Introductory Physics I
or PHY 010	General Physics I
PHY 012	Introductory Physics Laboratory I
PHY 021	Introductory Physics II
or PHY 013	General Physics II
PHY 022	Introductory Physics Laboratory II
Total Credits		65-67

¹: MATH 012 may be substituted by any statistics course with the approval of the department chair.

Model Roster When Path A is Followed for the B.S. in Chemistry degree programs

The strongest background includes Honors Chemistry (CHM 040 & 041) and the higher level Mathematics and Physics courses. The sequence below illustrates one pathway to achieve all required courses in the proper sequence. While the schedule below is ideal, MANY students start with different courses in their first year. It is possible to change into a B.S. in Chemistry degree program in a later semester, but consultation with a Major Advisor will be required. If a B.S. in Chemistry degree program is one of your options, stay in the MATH 21, 22, 23 sequence, and take Physics 11 and 21 instead of the "lower level" sequences (MATH 51&52, Physics 10&13).

First Year	Credits
College Seminar	3-4
CHM 040	4
CHM 041	4
MATH 021	4
MATH 022	4
PHY 011	4
PHY 012	1
WRT 001	3
WRT 002	3
	30-31
Second Year	Credits
CHM 110 & CHM 111	4
CHM 112 & CHM 113	4
PHY 021 & PHY 022	5
MATH 023	4
MATH 043	3
ENGR 010 or CSE 012	2
distribution requirements - free electives	9
	31
Total Credits: 61-62

Note that some concentrations would insert courses such as MATH 012, BIOS 041/BIOS 042 (B.S. Pharmaceutical Chemistry or B.S. in Biochemistry), etc., which may require moving some courses to later years. The non-B.S. in Chemistry degree programs can substitute the lower level MATH and PHYSICS courses as well.

junior year/senior year (30-32 credits each year)

Each student will need to meet with a Major Advisor in order to formulate the courses to be taken. There are a couple of sequencing issues, but if the full year of organic chemistry has been completed by the Fall of the third year, then the last two years are relatively easy to schedule to complete all required courses. Even if organic chemistry has not been completed by then, it is possible to complete everything in the remaining two years, but the course sequences becomes almost fixed in terms of when each course is taken.

Model Roster When Path B is Followed - Pharmaceutical Chemistry and Biochemistry

First Year	Credits
College Seminar	3-4
CHM 040	4
CHM 041	4
MATH 051	4
MATH 052	3
PHY 010	4
PHY 012	1
WRT 001	3
WRT 002	3
	29-30
Second Year	Credits
CHM 110 & CHM 111	4
CHM 112 & CHM 113	4
PHY 013 & PHY 022	4
MATH 043	3
distribution requirements - free electives	15
	30
Total Credits: 59-60

Note that some concentrations would insert courses such as MATH 012, BIOS 041/BIOS 042(B.S. Pharmaceutical Chemistry or B.S. in Biochemistry), etc., which may require moving some courses to later years. The non-B.S. in chemistry degree programs can substitute the lower level MATH and PHYSICS courses.

junior year/senior year (30-32 credits EACH YEAR)

Each student will need to meet with a Major Advisor in order to formulate the courses to be taken. There a couple of sequencing issues, but if the full year of organic chemistry has been completed by the Fall of the third year, then the last two years are relatively easy to schedule to complete all required courses.

B.S. Degree in Chemistry, College of Engineering & Applied Science

Summary of Requirements

The Chemistry and collateral courses for the ACS Certified Degree in Chemistry is identical in both colleges, in terms of the specific courses required. The B.S. in Chemistry degree in the Rossin College of Engineering and Applied Sciences requires both the higher level MATH and PHYSICS courses (MATH 21, 22, & 23, PHYS 11 & 21) but the college distribution requirements are a little different from those in the College of Arts and Sciences.

College distribution		24
Physics, math, and computing		28
Chemistry		46
Unrestricted electives		25
Total Credits		123

CHM 040	Honors General Chemistry I	4
or CHM 030	Introduction to Chemical Principles
CHM 041	Honors General Chemistry II	4
or CHM 031	Chemical Equilibria in Aqueous Systems
CHM 110 & CHM 111	Organic Chemistry I and Organic Chemistry Laboratory I	4
CHM 112 & CHM 113	Organic Chemistry II and Organic Chemistry Laboratory II	4
CHM 307	Advanced Inorganic Chemistry	3
CHM 332	Analytical Chemistry	3
CHM 334	Advanced Chemistry Laboratory I	3
CHM 335	Advanced Chemistry Laboratory II	3
CHM 341	Molecular Structure, Bonding and Dynamics	3
CHM 342	Thermodynamics & Kinetics	3
CHM 343	Physical Chemistry Laboratory	2
CHM 351	Professional Development Seminar	2
CHM 371	Elements of Biochemistry I	3
CHM 375	Research Chemistry Laboratory	2
Advanced Chemistry Elective Requirement
Select one course from two of the three areas listed below:		6
Analytical Chemistry (CHM 350) ¹
CHM 336	Clinical Chemistry
CHM 356	Spectral Analysis
CHM 388	Polymer Characterization
Biochemistry (CHM 350) ¹
CHM 323	Chemical Biology
CHM 362	Molecular Biophysics
CHM 365	Protein Separation & Biophysical Analysis
CHM 372	Elements of Biochemistry II
CHM 373	Lipids and Membranes
Inorganic Chemistry (CHM 350) ¹
CHM 305	Organometallic Chemistry
CHM 337	Crystallography and Diffraction
CHM 340	Solid-State Chemistry
CHM 364	Bioinorganic Chemistry
Collateral Requirements
MATH 021	Calculus I	4
MATH 022	Calculus II	4
MATH 023	Calculus III	4
MATH 205	Linear Methods	3
PHY 011 & PHY 012	Introductory Physics I and Introductory Physics Laboratory I	5
PHY 021 & PHY 022	Introductory Physics II and Introductory Physics Laboratory II	5
Select one from the following:		2-4
ENGR 010	Applied Engineering Computer Methods
CSE 003	Introduction to Programming, Part A
CSE 007	Introduction to Programming
Total Credits		76-78

¹: CHM 350 may be applied to any one of the three areas, provided it is for a 3 credit lecture course and the particular section has been identified to fit into one of these three areas based on course content. CHM 350 may be repeated for credit if a different topic is offered, and if appropriate, a second CHM 350 section may count under a different area.

Accelerated combined B.S. - M.S. degree options in chemistry

Individual degree paths can be designed to earn either the B.S. or both BS. and M.S. degrees in Chemistry over a reduced or accelerated time frame. A discussion with the Chemistry faculty advisor during the first academic year is required to successfully complete any of the following options:

If you have more than 20 credits total of AP or transfer courses, it may be possible to earn the B.S. in three years and the M.S. in four. This path may require up to two summers of courses and/or research for most students.
If you have 30 or more AP or transfer credits, then it may be possible to be supported as a Teaching Assistant or Research Assistant during the fourth year as a graduate student to finish the M.S. degree, although such support is not guaranteed. The B.S. degree must be completed in three years, and up to two summers of courses and/or research may be required.
If you have limited or no AP or transfer credits, then two paths are available: A) A five year path is possible with one summer of research work after the B.S. degree is finished in four years. B) A five year path with support during the fifth year as a TA or RA may be possible if courses are excluded from the undergraduate degree (possibly requiring course overloads), and one summer of research is generally required, but support is not guaranteed.

Accelerated B.S. degree options are also possible for some students. See the Chemistry faculty advisor to develop a customized program for your situation. A discussion as early as possible is best for determining which options may be suitable.

B.S. in Biochemistry

An interdepartmental B.S. in Biochemistry major is offered in the College of Arts and Sciences. Faculty in both Chemistry (Glover, and Thévenin) and Biological Sciences (Lowe-Krentz, Iovine and Behe) serve as advisors depending on student interest. Please see the section on Biochemistry for details of the major.

Minor in Chemistry

A minor in chemistry may be achieved by completing the following requirements:

CHM 031	Chemical Equilibria in Aqueous Systems ¹	4
or CHM 041	Honors General Chemistry II
CHM 110 & CHM 111	Organic Chemistry I and Organic Chemistry Laboratory I	4
CHM 332	Analytical Chemistry	3
CHM 342	Thermodynamics & Kinetics ²	3
CHM 343	Physical Chemistry Laboratory ³	2
Total Credits		16

1 Prerequisite of ( CHM 030 or CHM 040) and corequisite of (MATH 21 or MATH 31 or MATH 51 or MATH 76)

2. Prerequisites of (CHM 031 or CHM 041) and MATH 021 or MATH 51) and (MATH 022 or MATH 32 or MATH 52) and (PHY 013 or PHY 021).

3. Prerequisite of CHM 342.

4. Students who wish to minor in chemistry but whose major program requires more than one of the above courses may achieve the minor with substitutions approved by the department chair.

Graduate Programs in Chemistry

The Department of Chemistry offers graduate studies leading to two advanced degrees. Doctor of philosophy degrees in Chemistry and in Polymer science and engineering may be obtained by study and research in any appropriate area of chemistry.

The following information on admissions, proficiency examinations and other policies applies to doctor of philosophy degrees in chemistry.

Admission to graduate study in chemistry assumes that a student has met, or is willing to meet though further study, minimum undergraduate requirements for a bachelor’s degree in chemistry. This would include (beyond two semesters of introductory chemistry) two semesters of organic chemistry, two semesters of physical chemistry, two semesters of analytical chemistry and one semester of inorganic chemistry. A promising student whose degree is in a field related to chemistry (e.g., biology, chemical engineering) may be admitted to graduate study in chemistry provided that any deficiencies in basic chemistry preparation are made up in the first year of graduate study, noting that some of the courses required for this may not carry graduate credit.

The Chemistry Department administers proficiency examinations at the undergraduate level upon matriculation to Lehigh. Information on the examinations will be sent to each student several months in advance of matriculation. It is expected that each student will prepare diligently for these tests. A Ph.D. candidate must show proficiency in the areas tested. An incoming student who fails one or more of the examinations will have two additional opportunities to demonstrate proficiency by re-taking the examination(s). The student is highly encouraged to meet with the Graduate Advising Director to determine the best course of action in light of the exam performance and projected area of study. The student may prepare for the examination(s) by self-study and/or enrolling in or auditing of appropriate courses, and is strongly encouraged to seek faculty advice on preparing to retake any exam.

Doctor of Philosophy Degree

Completion of a doctor of philosophy degree program normally requires a minimum of four years of full time work after entrance with a bachelor’s degree. There are few specific course credit requirements for the Ph.D.; however, approved degree programs generally have at least 26 hours of course work. A minimum of 15 credits must be obtained in the Department of Chemistry. Thus, the program consists of approximately one-third formal course work and two-thirds independent study and research. There is a one-credit seminar requirement (CHM 481). After Ph.D. proficiency has been established and the research advisor selected (this must be done by the end of the first semester in residence), the major hurdle is the general doctoral examination in the student’s area of concentration. This exam must be passed by the end of 2 1/2 years of residence. If this hurdle is surmounted, the remaining time is spent completing (and ultimately defending) the dissertation research under the guidance of the research advisor and the dissertation committee.

Chemistry, PhD

Course Work		18
CHM 421	Chemistry Research	6
CHM 481	Chemistry Seminar	1
Total Credits ¹		26

¹: A minimum of 15 credits must be obtained in the Department of Chemistry.

Current Research Projects

Current research projects of interest are listed below.

Analytical Chemistry

Biosensors; microfluidic platforms; electroanalytical chemistry.

Biochemistry

Membrane protein interactions; structural characterization of membrane proteins; production of membrane proteins; biophysical characterization of membrane proteins; biomaterials; multi-drug resistance; selective drug delivery; anti-cancer therapy; antibiotic drug discovery; cell surface remodeling; immunotherapy; activity based probes; fluorescence assay development.

Inorganic Chemistry

Synthesis, characterization, and reactivity of transition metal complexes and nano particles; coordination chemistry and molecular self-assembly at metal surfaces and semi-metal surfaces; electrochemistry at metal, semi-metal, and oxide-coated electrodes; synthesis and characterization of mesoporous solids from transition metal and main-group element precursors; applications of mesoporous solids for carbon sequestration; formation of multilayered thin films of inorganic and organic-inorganic hybrid materials; and application of lanthanide catalysis in organic synthesis.

Materials and Polymer Chemistry

Inorganic and organometallic chemistry in the synthesis of thin-film materials; synthesis at and dynamics of polymer interfaces; acoustic, optical, permeability, dielectric and mechanical behavior of thin films; laser light scattering and small-angle X-ray scattering studies on polymer solutions; polyelectrolytes and ion-containing solutions; nanofabrications in polymer systems; organic-inorganic hybrid solid state materials; synthesis and characterization of novel mesoporous materials; characterization of semiconducting material

Organic Chemistry

Chemical models for biochemical reactions; chemistry of monolayers and organized molecule assemblages; drug carriers; synthetic ion conductors; organometallic reaction mechanisms; organofluorine chemistry; protein folding and renaturation; molecular recognition; calorimetry; electrochemical studies of electron transfer reactions; synthetic methods development.

Physical Chemistry

Chemistry at surfaces and interfaces of polymers, electrodes, thin films, and biosensors using an array of surface sensitive methods: spectroscopic ellipsometry, scanning probe microscopy, angle resolved X-ray photo electron spectroscopy, electrochemistry, and quartz crystal microbalance; nanomechanics; intermolecular interactions in soft matter; single-molecule force spectroscopy; chemically sensitive imaging at nanoscale; development of optics-based tools for chemical analysis; femtosecond ultra-fast spectroscopy; investigation of charge transfer in energy materials; spectroscopy; transient absorption spectroscopy; time-resolved photoluminescence; proton-coupled electron transfer reactions.

Major Instrumentation

Chemistry research spans all areas: analytical, biochemistry, inorganic, organic, and physical. Special equipment available for graduate research in chemistry is as follows.

Research facilities

GC-MS, MALDI-TOF-MS, HPLCs, GCs, ultracentrifuges, cold rooms, cell disintegrator, zone and disc electrophoresis apparatus, column chromatograph, autoclave, freezers (-80C), rotary vaporator, Milli-Q water purification system, shaking heated water baths, spectropolarimeter with circular dichroism capability. Cell culture facilities – complete with optical microscopes having fluorescent and photographic capabilities. Electron optical facilities – transmission electron microscopy with x-ray fluorescence analysis capability, scanning electron microscope, and scanning electron microprobe. Gas chromatographs. Liquid chromatographs – high performance for analytical and preparative work. NMR spectrometers – 400 MHz for both solids and solutions, and 500 MHz for solutions with an enhanced sensitivity multinuclear cyroprobe. Photochemistry equipment – lamps and filters for selected wavelength work. Polarographs, chronopotentiometers, electrophoresis apparatus, electrochemical impedance, electrochemical scanning tunneling microscope, potentiostats, and rotating disk electrode. Portable data interface (8-channel 50 KHz), digital readout polarimeter, Vibron elastoviscometers, differential refractometer.

Spectrometers

UV/visible double beam automated, fluorescence, UV/visible/near IR, Fourier transform IR with diffuse reflectance, photoacoustic and attenuated reflectance capability, and GC mass spectrometers. Surface analysis facilities – rotating anode high-sensitivity high-energy resolution ESCA with imaging capability (ESCA is equipped with automated angular data acquisition). Surface science facility – Low energy electron diffraction (LEED), photocorrelation spectroscopy for submicron particle analysis. Ellipsometer, contact angle capabilities, gas adsorption apparatus (BET), atomic force microscope, instructional scanning tunneling microscope, and light scanning. Microcalorimeter (flowing with UV and refractive index detectors), differential scanning calorimeter (DSC).

Courses

CHM 030 Introduction to Chemical Principles 0,4 Credits

An introduction to important topics in chemistry: atomic structure, properties of matter, chemical reactions, energy, structure and bonding in organic and inorganic compounds. The course features a lecture tightly linked to a three-hour studio experience that combines laboratory work and recitation.
Attribute/Distribution: LS, NS, NW, Q

CHM 031 Chemical Equilibria in Aqueous Systems 0,4 Credits

An introduction to: intermolecular forces and their influence on physical properties and phase behavior; chemical kinetics; thermodynamics in chemical systems; and electrochemistry. The course includes a detailed treatment of equilibria in aqueous solutions, including acid-base, precipitation-solubility, metal-ligand, oxidation-reduction and distribution equilibria. The laboratory work emphasizes the qualitative and quantitative analysis of equilibria in aqueous media. Three lectures and one three-hour laboratory period.
Prerequisites: (CHM 030 or CHM 040) and (MATH 021 or MATH 031 or MATH 051 or MATH 076)
Attribute/Distribution: NS, NW, Q

CHM 040 Honors General Chemistry I 0,4 Credits

A first-semester course in chemistry for students planning to major in chemistry, biochemistry, chemical engineering, materials science, or other chemistry-related fields. Chemical and physical properties, structures, bonding concepts, and quantitative analysis. Laboratory includes synthesis, separation and analysis procedures; computer applications to chemistry. Three lectures and one three-hour laboratory period.
Attribute/Distribution: NS, NW, Q

CHM 041 Honors General Chemistry II 0,4 Credits

Continuation of Chemistry 40. Three lectures and one three-hour laboratory period.
Prerequisites: (CHM 040 or CHM 030) and (MATH 021 or MATH 031 or MATH 051 or MATH 075)
Can be taken Concurrently: MATH 021, MATH 031, MATH 051, MATH 075
Attribute/Distribution: NS, NW, Q

CHM 110 Organic Chemistry I 0,3 Credits

Systematic survey of the typical compounds of carbon, their classification, and general relations; study of synthetic reactions.
Prerequisites: CHM 031 or CHM 041
Attribute/Distribution: NS

CHM 111 Organic Chemistry Laboratory I 1 Credit

Preparation of pure organic compounds. Modern techniques of characterization.
Prerequisites: CHM 031 or CHM 041 or CHM 110
Can be taken Concurrently: CHM 110
Attribute/Distribution: NS, Q

CHM 112 Organic Chemistry II 0,3 Credits

Continuation of CHM 110.
Prerequisites: CHM 031 or CHM 041 or CHM 110
Attribute/Distribution: NS

CHM 113 Organic Chemistry Laboratory II 1 Credit

Continuation of Organic Chemistry Laboratory I.
Prerequisites: CHM 030 or CHM 040 and (CHM 031 or CHM 041 or CHM 110) and CHM 112
Can be taken Concurrently: CHM 112
Attribute/Distribution: NS, Q

CHM 177 Introduction to Research 1-2 Credits

For advanced freshmen and sophomore chemistry majors. Consent of department chair required.
Repeat Status: Course may be repeated.
Attribute/Distribution: NS, NW, Q

CHM 194 Physical Chemistry for Biological Sciences 3 Credits

The principles and applications of physical chemical concepts to systems of biological interest, including the gas laws, thermodynamics of metabolic reactions, colligative properties, electrochemical equilibria, reaction kinetics and enzyme catalysis, and transport of macromolecules and viruses.
Prerequisites: (CHM 030 or CHM 040) and (CHM 031 or CHM 041)
Attribute/Distribution: NS, Q

CHM 250 Special Topics 1-4 Credits

Selected topics in chemistry. Consent of instructor required.
Repeat Status: Course may be repeated.

CHM 300 Apprentice Teaching 3 Credits

Consent of instructor required.
Repeat Status: Course may be repeated.

CHM 305 Organometallic Chemistry 3 Credits

The chemistry of compounds containing bonds between carbon and the transition metals. Topics include the synthesis, characterization, and electronic structure of organometallic compounds, and mechanistic studies of their reactions. A description of common ligands and their bonding is covered, as well as applications of organometallic chemistry in organic synthesis and catalysis.
Prerequisites: CHM 112
Attribute/Distribution: NS

CHM 307 Advanced Inorganic Chemistry 3 Credits

Introduction to transition metal complexes; theories of bonding; kinetics and mechanisms of transition metal complex reactions; and selected aspects of organometallic chemistry. .
Prerequisites: CHM 031 or CHM 041
Attribute/Distribution: NS, NW, Q

CHM 323 Chemical Biology 3 Credits

Chemical biology is a discipline at the interface of organic and biological chemistry. It entails the design, synthesis, and evaluation of probes, substrates, and materials for the study of biological systems using chemical principles. Chemical biology can also take inspiration from biological systems for the design and synthesis of novel molecules and materials for non-biological applications. The class is designed to be an introduction to chemical biology for upper-level undergraduates and graduate students.
Prerequisites: CHM 112 and (BIOS 371 or CHM 371)

CHM 332 Analytical Chemistry 3 Credits

Theory and practice of chemical analysis. Principles of quantitative separations and determinations; theory and application of selected optical and electrical instruments in analytical chemistry; interpretation of numerical data, design of experiments, solute distribution in separation methods.
Prerequisites: (CHM 031 or CHM 041) and CHM 110
Attribute/Distribution: NS, Q

CHM 334 Advanced Chemistry Laboratory I 0,3 Credits

Exploration of synthetic methods and analysis techniques for inorganic and organic compounds. Determination of product structures and quantitative analysis using modern chemical analysis techniques, including NMR, GC-MS, GC, HPLC, FT-IR, and Electrochemistry.
Prerequisites: (CHM 110 and CHM 111 and CHM 112 and CHM 113 and CHM 332)
Can be taken Concurrently: CHM 332
Attribute/Distribution: Q, W

CHM 335 Advanced Chemistry Laboratory II 0,3 Credits

Continuation of CHM 334.
Prerequisites: (CHM 334)
Attribute/Distribution: Q, W

CHM 336 Clinical Chemistry 3 Credits

Applications of analytical chemistry to clinical problems. Discussion of methods in common use and the biochemical/medical significance of the results.
Prerequisites: CHM 031 or CHM 041 or CHM 332 or CHM 112
Attribute/Distribution: NS, Q

CHM 337 Crystallography and Diffraction 3 Credits

Introduction to crystal symmetry, point groups, and space groups. Emphasis on materials characterization by Xray diffraction and electron diffraction. Specific topics include crystallographic notation, stereographic projections, orientation of single crystals, textures, phase identification, quantitative analysis, stress measurement, electron diffraction, ring and spot patterns, convergent beam electron diffraction (CBED), and space group determination. Applications in mineralogy, metallurgy, ceramics, microelectronics, polymers, and catalysts. Lectures and laboratory work. Prerequisites may be waived if student has senior standing in chemistry.
Prerequisites: CHM 031 or CHM 041 or MAT 203 or EES 131
Attribute/Distribution: NS

CHM 340 Solid-State Chemistry 3 Credits

This solid state chemistry course will introduce students into symmetry of extended solids, X-ray crystallography of solids, crystal structures, band theory, electronic and ionic conductivity in solids, defects in solids, silicate chemistry and nanoporous solids.
Prerequisites: CHM 031 or CHM 041
Attribute/Distribution: NS, NW, Q

CHM 341 Molecular Structure, Bonding and Dynamics 3 Credits

Nature of chemical bonding as related to structure and properties of molecules and extended systems. Quantum chemistry of atoms and molecules applied to chemical transformations and spectroscopic transitions. Symmetry analysis and selections rules. Interpretation of electronic, vibrational and rotational spectra.
Prerequisites: (MATH 023 or MATH 033) and (PHY 021 or PHY 013) and (CHM 031 or CHM 041)
Attribute/Distribution: NS, Q

CHM 342 Thermodynamics & Kinetics 3 Credits

Development of the principles of classical and statistical thermodynamics and their application to chemical systems. In classical thermodynamics emphasis will be on systems in which composition is of major concern: solutions, chemical and phase equilibria. Kinetic theory of gases; chemical reaction kinetics; chemical reaction dynamics.
Prerequisites: (CHM 031 or CHM 041) and (PHY 013 or PHY 021) and (MATH 022 or MATH 032 or MATH 052)
Attribute/Distribution: Q

CHM 343 Physical Chemistry Laboratory 2 Credits

Laboratory studies that illustrate and extend the various fields of study in experimental physical chemistry as discussed in CHM 341 and CHM 342. This course fulfills the junior year writing intensive course requirement in CAS.
Prerequisites: CHM 194 or CHE 210 or CHM 342
Attribute/Distribution: NS, W, WRIT

CHM 346 Photochemistry of Consequence 3 Credits

Photochemistry involves using photons (light from the sun) to drive critical chemical reactions and is attractive because of its application to solar energy. Fundamental processes in photochemistry will be covered . Topics will include: energy transfer, electron transfer, proton-coupled electron transfer processes and their applications to biological systems.
Prerequisites: CHM 031 or CHM 041
Attribute/Distribution: NS

CHM 350 Special Topics 1-3 Credits

Selected advanced topics in chemistry.
Repeat Status: Course may be repeated.
Attribute/Distribution: NS

CHM 351 Professional Development Seminar 2 Credits

Topics for the developing professional chemist include lab safety, using a laboratory notebook, searching the scientific literature, reading and writing scientific papers, ethics, and developing both a poster and an oral presentation. Students will present their own poster and a short talk on the same subject. Each student will write his/her own resume and participate in a mock interview session.
Attribute/Distribution: NS

CHM 356 Spectral Analysis 3 Credits

Use of data from nuclear magnetic residence, infrared, ultraviolet, and mass spectrometric techniques for the determination of structure of organic compounds. Emphasis on information from one- and two-dimensional proton and carbon NMR, and a mechanistic interpretation of data from mass spectrometry.
Prerequisites: CHM 112

CHM 357 Organic Reaction Mechanisms 3 Credits

Intensive in class problem solving that involves the formulation of reasonable reaction mechanisms for complex multistep pathways, i.e. organic transformations that proceed via highly energetic intermediates such as carbocations, carbanions, free radicals, carbenes, and nitrenes.
Prerequisites: CHM 112

CHM 358 Advanced Organic Chemistry 3 Credits

Reaction mechanism types and supporting physical-chemical data. Classes of mechanisms include elimination, substitution, rearrangement, oxidation-reduction, enolate alkylations, and others. Must have completed one year of organic chemistry.
Prerequisites: CHM 112
Attribute/Distribution: NS

CHM 362 Molecular Biophysics 3 Credits

This course focuses on the physical tools that exist to obtain information about biological macromolecules, with an emphasis on spectroscopic and imaging techniques (e.g., circular dichroism, fluorescence spectroscopy, FRET, BRET, calorimetry, analytical ultracentrifugation, X-ray crystallography, electron microscopy, dynamic light scattering, surface plasmon resonance). Lectures and discussion of research articles are used to illustrate the use of the different tools and methods.
Prerequisites: BIOS 371 or CHM 371
Attribute/Distribution: NS

CHM 364 Bioinorganic Chemistry 3 Credits

This course will cover inorganic chemistry as it relates to biology, with emphasis on how metal ions and cofactors are employed by biological systems. Topics will include metalloproteins, metal cofactors, and metals in medicine. Experimental methods used to study bioinorganic chemistry will also be discussed.
Prerequisites: CHM 371 or BIOS 371
Attribute/Distribution: NS

CHM 365 Protein Separation & Biophysical Analysis 3 Credits

Laboratory studies of techniques and principles used for the isolation, characterization, and biophysical analysis of proteins.
Prerequisites: BIOS 371 or CHM 371
Attribute/Distribution: NS

CHM 371 (BIOS 371) Elements of Biochemistry I 0,3 Credits

A general study of carbohydrates, proteins, lipids, nucleic acids and other biological substances and their importance in life processes. Protein and enzyme chemistry are emphasized. Must have completed one year of organic chemistry.
Prerequisites: CHM 112
Attribute/Distribution: NS

CHM 372 (BIOS 372) Elements of Biochemistry II 3 Credits

Dynamic aspects of biochemistry: enzyme reactions including energetics, kinetics and mechanisms, metabolism of carbohydrates, lipids, proteins and nucleic acids, photosynthesis, electron transport mechanisms, coupled reactions, phosphorylations, and the synthesis of biological macromolecules.
Prerequisites: BIOS 473 or ((BIOS 371 or CHM 371) and BIOS 041)
Attribute/Distribution: NS

CHM 373 Lipids and Membranes 3 Credits

The study of lipids and lipid membranes similar to those found in mammalian cells including methods of synthesis, surface activity, bilayer and micellar structures, lipid mixing, fluidity, permeability and membrane stability. Special emphasis will be given to the current evidence for and against the lipid raft hypothesis.
Prerequisites: BIOS 372 or CHM 372
Attribute/Distribution: NS

CHM 375 Research Chemistry Laboratory 1-3 Credits

An introduction to independent study or laboratory investigation under faculty guidance. Consent of instructor required.
Repeat Status: Course may be repeated.
Attribute/Distribution: NS, Q

CHM 376 Advanced Research Chemistry Laboratory 1-6 Credits

Advanced independent study or laboratory investigation under faculty guidance. Consent of faculty research supervisor.
Repeat Status: Course may be repeated.
Attribute/Distribution: NS, Q

CHM 377 (BIOS 377) Biochemistry Laboratory 0,3 Credits

Laboratory studies of the properties of chemicals of biological origin and the influence of chemical and physical factors on these properties. Laboratory techniques used for the isolation and identification of biochemicals.
Prerequisites: (BIOS 371 or CHM 371) and (BIOS 031 or BIOS 041)
Can be taken Concurrently: BIOS 371, CHM 371
Attribute/Distribution: NS

CHM 388 (CHE 388, MAT 388) Polymer Characterization 3 Credits

Description of molecular weight measurements using dilute solutions (solution viscosity, size exclusion chromatography, osmotic pressure, and light scattering). Introduction to polymer thermal analysis techniques such as differential scanning calorimetry (DSC) , dynamic mechanical analysis (DMA), and thermomechanical analyzer (TMA). Discussion of structure and morphology of polymers and polymer blends using nuclear magnetic resonance (NMR), infrared spectroscopy (IR), Raman spectroscopy, UV analysis, transmission electron microscopy (TEM), scanning electron microscopy (SEM), atomic force microscopy (AFM). Crystallinity measurements using SANS, SAXS, and WAXS.
Prerequisites: MAT 033 or MAT 204 or MAT 392 or MAT 393

CHM 389 Honors Project 1-6 Credits

Opportunity for Chemistry majors to pursue an Honors Project. Consent of instructor required.
Repeat Status: Course may be repeated.
Attribute/Distribution: Q, W

CHM 391 (CHE 391) Colloid and Surface Chemistry 3 Credits

Physical chemistry of everyday phenomena. Intermolecular forces and electrostatic phenomena at interfaces, boundary tensions and films at interfaces, mass and charge transport in colloidal suspensions, electrostatic and London forces in disperse systems, gas adsorption and heterogeneous catalysis.
Prerequisites: CHM 342
Attribute/Distribution: NS

CHM 393 (CHE 393, MAT 393) Physical Polymer Science 3 Credits

Structural and physical aspects of polymers (organic, inorganic, natural). Molecular and atomic basis for polymer properties and behavior. Characteristics of glassy, crystalline, and paracrystal-line states (including viscoelastic and relaxation behavior) for single-and multi-component systems. Thermodynamics and kinetics of transition phenomena. Structure, morphology, and behavior. Available to graduate and undergraduate students (with senior level standing) in CHE, CHEM or MAT.

CHM 394 (CHE 394) Organic Polymer Science I 3 Credits

Organic chemistry of synthetic high polymers. Polymer nomenclature, properties, and applications. Functionality and reactivity or monomers and polymers. Mechanism and kinetics of step-growth and chain-growth polymerization in homogenous and heterogenous media. Brief description of emulsion polymerization, ionic polymerization, and copolymerization. Must have completed one year of physical chemistry and one year of organic chemistry.
Prerequisites: CHM 031 or CHM 041 or CHM 110 or CHM 112 or CHM 342 or CHE 210
Attribute/Distribution: NS, Q

CHM 400 First Year Graduate Student Seminar 0 Credits

First year graduate student seminar course and introduction to research. Topics include: research opportunities in the department, introduction to instrumentation facilities, ethics in science, use of library facilities, effective teaching methods. Course may be repeated.
Repeat Status: Course may be repeated.

CHM 405 Organometallic Chemistry 3 Credits

The chemistry of compounds containing bonds between carbon and the transition metals. Topics include the synthesis, characterization, and electronic structure of organometallic compounds, and mechanistic studies of their reactions. A description of common ligands and their bonding is covered, as well as applications of organnometallic chemistry in organic synthesis and catalysis.

CHM 407 Advanced Inorganic Chemistry 3 Credits

Introduction to transition metal complexes; theories of bonding; kinetics and mechanisms of transition metal complex reactions; and selected aspects of organometallic chemistry. Must have completed one semester of physical chemistry and have CAS graduate student status.

CHM 421 Chemistry Research 1-6 Credits

Research in one of the following fields of chemistry: analytical, inorganic, organic, physical, polymer, biochemistry. A maximum of 6 credits total may be earned. Consent of the instructor is required.
Repeat Status: Course may be repeated.

CHM 423 Chemical Biology 3 Credits

CHM 426 Statistical Thermodynamics 3 Credits

Principles and applications of statistical mechanics to chemical problems. A study of the techniques for evaluating the properties of matter in bulk from the properties of molecules and their interactions.

CHM 427 Thermodynamics & Kinetics 3 Credits

Development of the principles of classical and statistical thermodynamics and their applications to chemical systems. In classical thermodynamics, emphasis will be on systems in which composition is of major concern: solutions, chemical and phase equilibria. Kinetic theory of gases; chemical reaction kinetics. Must have CAS graduate student status. This course cannot be taken by students who have already taken CHM 342.

CHM 434 Advanced Topics in Spectroscopy 3 Credits

Fundamentals of interactions of electromagnetic radiation with matter: electronic, vibrational, scattering based spectroscopies, instrumentation and signal processing. Advanced applications to the analysis of molecular structure and chemical processes including surface analysis, time-resolved spectroscopies, and ultrasensitive spectroscopic techniques.

CHM 436 Special Topics in Analytical Chemistry 1-3 Credits

Topics of contemporary interest in analytical chemistry.
Repeat Status: Course may be repeated.

CHM 438 Analytical Chemistry 3 Credits

Theory and practice of chemical analysis. Principles of quantitative separations and determinations; theory and application of selected optical and electrical instruments in analytical chemistry; interpretation of numerical data; design of experiments; solute distribution in separation methods. Must have CAS graduate student status.

CHM 443 (MAT 443) Solid-State Chemistry 3 Credits

CHM 444 Molecular Structure, Bonding and Dynamics 0,3 Credits

CHM 446 Photochemistry of Consequence 3 Credits

Photochemistry involves using photons (light from the sun) to drive critical chemical reactions and is attractive because of its application to solar energy. Fundamental processes in photochemistry will be covered. Topics will include: energy transfer, electron transfer, proton-coupled electron transfer processes and their applications to biological systems.

CHM 452 Advanced Organic Chemistry 3 Credits

Reaction mechanism types and supporting physical chemical data. Classes of mechanisms include elimination, substitution, rearrangement, oxidation reduction, enolate alkylations, and others. Must have completed one year of organic chemistry and have CAS graduate student status.

CHM 453 Heterocyclic Compounds 3 Credits

An intensive study of the syntheses, reactions and properties of heteroaromatic compounds including derivatives of thiophene, pyrrole, furan, indole, pyridine, quinoline, the azoles and the diazines all considered from the viewpoint of modern theories of structure and reaction mechanisms.
Prerequisites: CHM 358 or CHM 452

CHM 455 Organic Reactions 3 Credits

Intensive survey of modern synthetic organic chemistry from a mechanistic standpoint. Classical Namereactions, olefin synthesis, organometallic reagents in synthesis, Woodward-Hoffmann rules, electrocyclic processes, enolate chemistry, and related reactions.
Prerequisites: or CHM 452, CHM 358 or CHM 452

CHM 456 Spectral Analysis 3 Credits

Use of data from nuclear magnetic resonance, infrared, ultraviolet, and mass spectrometric techniques for the determination of structure of organic compounds. Emphasis on information from one- and two-dimensional proton and carbon NMR, and a mechanistic interpretation of data from mass spectrometry.

CHM 457 Organic Reaction Mechanisms 3 Credits

CHM 458 Topics in Organic Chemistry 1-3 Credits

An intensive study of limited areas in organic chemistry.
Repeat Status: Course may be repeated.

CHM 462 3 Credits

CHM 464 Bioinorganic Chemistry 3 Credits

CHM 465 Protein Separation & Biophysical Analysis 3 Credits

Laboratory studies of techniques and principles used for the isolation, characterization, and biophysical analysis of proteins.
Attribute/Distribution: NS

CHM 472 (BIOS 472) Lipids and Membranes 3 Credits

CHM 473 (BIOS 473) Principles of Biochemistry I 3 Credits

Study of proteins, carbohydrates, lipids, nucleic acids and other biological substances. Protein and enzyme chemistry are emphasized. Must have completed one year each of general chemistry and organic chemistry.

CHM 475 Advanced Topics in Chemistry 1 Credit

Audiovisual courses in topics such as acid-base theory, NMR, chromatography, electroanalytical chemistry and mass-spectroscopy interpretation; course material obtained from the American Chemical Society.
Repeat Status: Course may be repeated.

CHM 477 (BIOS 477) Topics In Biochemistry 1-3 Credits

Selected areas of biochemistry, such as mechanisms of enzyme action, new developments in the chemistry of lipids, nucleic acids, carbohydrates and proteins. Must have completed one semester of biochemistry.
Repeat Status: Course may be repeated.

CHM 481 Chemistry Seminar 1 Credit

Student presentations on current research topics in the student’s discipline but not on subjects close to the thesis. A one-hour presentation and attendance at other presentations are required for credit.
Repeat Status: Course may be repeated.

CHM 482 (CHE 482, MAT 482) Mechanical Behaviors of Polymers 3 Credits

Mechanical behavior of polymers. Characterization of experimentally observed viscoelastic response of polymeric solids with the aid of mechanical model analogs. Topics include time-temperature superposition, experimental characterization of large deformation and fracture processes, polymer adhesion, and the effects of fillers, plasticizer, moisture, and aging on mechanicial behavior.

CHM 483 (CHE 483, MAT 483) Emulsion Polymers 3 Credits

Fundamental concepts important in manufacture, characterization, and application of polymer latexes. Topics include colloidal stability, polymerization mechanisms and kinetics, reactor design, characterization of particle surfaces, latex rheology, morphology considerations, polymerization with functional groups, film formation and various application problems.

CHM 485 (CHE 485, MAT 485) Polymer Blends 3 Credits

Synthesis, morphology, and mechanical behavior of polymer blends. Polymer/polymer miscibility and thermodynamics of mixing of polymer/solvent and polymer/polymer blends. Prediction of miscibility using various theoretical models and methods that can be used to help enhance miscibility (H bonding etc.). Methods to enhance the compatibility of polymer/polymer blends (e.g., block copolymers, ternary addition, IPNs), etc.). Types of polymer blends. Must have completed any introductory polymer course or equivalent.

CHM 487 Topics in Colloid and Surface Chemistry 3 Credits

Applications of colloid chemistry; special topics in surface chemistry. Lectures and seminar.
Repeat Status: Course may be repeated.

CHM 488 Advanced Topics in Physical Chemistry 1-3 Credits

Advanced topics in physical chemistry, such as photochemistry and molecular beam dynamics, Fourier transform spectroscopy, kinetics of rapid reactions, theory of magnetic resonance, liquids and solutions. Topic changes almost every time it is offered.
Repeat Status: Course may be repeated.

CHM 489 Organic Polymer Science II 3 Credits

Continuation of CHM 394. Theory and mechanism of ionic vinyladdition chaingrowth polymerization. Chain copolymerization by radical and ionic mechanism. Mechanism of ring-opening polymerization, stereochemistry of polymerization including ionic, coordination, and Ziegler-Natta mechanisms. Reactions of polymers, including crosslinking, reaction of functional groups, graft and block copolymers, and polymer carriers and supports.

CHM 490 Thesis 1-6 Credits

Repeat Status: Course may be repeated.

CHM 492 (CHE 492, MAT 492) Topics in Polymer Science 3 Credits

Intensive study of topics selected from areas of current research interest such as morphology and mechanical behavior, thermodynamics and kinetics of crystallization, new analytical techniques, molecular weight distribution, non-Newtownian flow behavior, second-order transition phenomena, novel polymer structures. Credit above three hours is granted only when different material is covered.

CHM 494 Quantum Chemistry 3 Credits

Principles and applications of quantum mechanics to chemical problems. Applications to chemical bonding, molecular structure, reactivity and spectroscopy.

CHM 499 Dissertation 1-15 Credits

Repeat Status: Course may be repeated.